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July 9, 2026 | 5pm ET (Virtual)

Watch the recording of the Annual Donald and Barbara Zucker Healthy Aging Lecture featuring Dr. Paul García, MD, PhD

In “Postoperative Delirium and the Acceleration of Brain Aging: Can We Stop the Snowball?”, Dr. García explores how perioperative brain changes can precipitate delirium and contribute to long-term cognitive decline—especially in older adults. Drawing on NIH- and VA-funded research, he discusses EEG biomarkers of anesthetic state, nociception, emergence from anesthesia, and practical strategies to personalize anesthetic care and improve postoperative recovery. Hosted by the Northwell Roybal Center for Personalized Trials, this talk bridges cutting-edge neuroscience with actionable clinical insights for clinicians, researchers, caregivers, and patients focused on perioperative brain health. Watch now to learn how targeted monitoring and individualized care pathways may help prevent delirium and slow the cascade of brain aging after surgery.




Dr. Paul García, MD, PhD is a Professor of Anesthesiology at Columbia University. 


Dr. García’s research has been funded by the NIH, the U.S. Department of Veterans Affairs, and private foundations. His work focuses on perioperative neuroscience and the development of clinically actionable approaches to brain monitoring. He has led clinical investigations examining electroencephalographic (EEG) biomarkers of anesthetic state, nociception, emergence from anesthesia, postoperative delirium, and cognitive recovery after surgery. His research seeks to identify neurophysiologic signatures that can guide individualized anesthetic care and improve perioperative outcomes. Dr. García’s interests center on multidisciplinary clinical research that informs evidence-based practice and advances perioperative brain health across diverse surgical populations.


This annual series, hosted by the Northwell Roybal Center for Personalized Trials, features leading researchers at the intersection of aging-related topics including Alzheimer Disease and related dementias and physical activity.

Applications Open July 6, 2026

Issued by: The Edward R. Roybal Centers for Translational Research on Aging 

Sponsored by: National Institute on Aging (NIA) 

LOI Deadline: October 1, 2026

Full Application Deadline: December 7, 2026



Northwell Roybal Center for Personalized Trials

Center Focus: Walking interventions for patients with mild cognitive impairment or dementia

 

The Roybal Program will be accepting applications to fund fully powered, randomized clinical trials on behavioral interventions in aging. Applicants must apply the NIH Stage Model as a conceptual framework and clearly articulate a plan for how their trial will progress through the NIH Stage Model.

 

All clinical trials must have adequate statistical power to test mechanism of behavior change and/or efficacy of the intervention.

July 9, 2026 | 5pm ET (Virtual)

Dr. Paul García, MD, PhD is a Professor of Anesthesiology at Columbia University. 


Dr. García’s research has been funded by the NIH, the U.S. Department of Veterans Affairs, and private foundations. His work focuses on perioperative neuroscience and the development of clinically actionable approaches to brain monitoring. He has led clinical investigations examining electroencephalographic (EEG) biomarkers of anesthetic state, nociception, emergence from anesthesia, postoperative delirium, and cognitive recovery after surgery. His research seeks to identify neurophysiologic signatures that can guide individualized anesthetic care and improve perioperative outcomes. Dr. García’s interests center on multidisciplinary clinical research that informs evidence-based practice and advances perioperative brain health across diverse surgical populations.



This annual series, hosted by the Northwell Roybal Center for Personalized Trials, features leading researchers at the intersection of aging-related topics including Alzheimer Disease and related dementias and physical activity.

Supported by the National Institute On Aging of the National Institutes of Health under Award Number P30AG063786

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