Who Are We?
The Northwell Roybal Center for Personalized Trials works to develop behavioral interventions and adequately powered clinical trial results that can be translated into scalable, implementable interventions through innovative mechanisms of behavior change, behavior change theories and techniques, and innovative personalized methods.
Our Current Focus
1
Comprehensively and creatively test several Stage I-V behavior-change interventions to initiate and maintain physical activity in caregivers of those living with AD/ADRD or those with AD/ADRD 
2
Contribute to the science of basic behavior change by testing behavior change theories, techniques, and mechanisms for promoting physical activity in caregivers and those with AD/ADRD 
3
Provide trial and future program of research support to under-represented investigators
4
Build an evidence-based, implementable suite of personalized behavior change interventions and measures of mechanisms of action for promoting physical activity in caregivers and those with AD/ADRD
Our Team
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Karina Davidson, PhD, MASc
Site Principal Investigator and Administrative Core Lead
Dr. Davidson currently holds the title of SVP, Research at Northwell Health, and leads the Institute of Health System Science in the Feinstein Institutes for Medical Research. Dr. Davidson has over 25 years of experience serving in leadership roles focused on the advancement of scientific and patient care missions through the generation and implementation of research-based evidence.
Maria Carney, MD, MACP
Safety Monitor
Dr. Carney is Chief of the Division of Geriatrics and Palliative Medicine and Medical Director of Continuing Care at Northwell Health, as well as Professor in the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. She is board-certified in internal medicine, geriatric medicine, and hospice/palliative medicine and the former Commissioner of Health for Nassau County in Long Island.
Mark Butler, PhD
Principal Investigator, Co-Investigator, and Behavioral Intervention Development Core Co-Lead
Dr. Butler is an Assistant Professor in the Institute of Health System Science at the Feinstein Institutes for Medical Research. He is a clinical psychologist with specialized training and expertise in quantitative methods and personalized, n-of-1 methods. Dr. Butler has extensive experience in behavioral intervention trials for health behaviors, including BCT intervention trials to increase physical activity. Further, Dr. Butler has studied the psychosocial predictors and correlates of health behaviors. Most important to the work of the BID Core, Dr. Butler has extensive experience in personalized behavioral trials, particularly with personalized trials for health promoting behaviors. Dr. Butler also has expertise in identifying mechanisms of health behaviors and behavioral interventions.
Liron Sinvani, MD, AGSF, FHM
Behavioral Intervention Development Core Co-Lead
Dr. Sinvani is a board-certified hospitalist with geriatrics training, professor of medicine in the Department of Medicine, Division of Hospital Medicine and Division of Geriatrics and Palliative Care at the Zucker School of Medicine/Northwell Health, associate professor at the Institute of Health System Science at the Feinstein Institutes for Medical Research, director of the Geriatrics Hospitalist Service at Northwell Health, and director of research for the department of research at Northwell Health. Dr. Sinvani is an internist and geriatrician who has served as principal investigator investigating factors associated with cognitive impairment, delirium, dementia, and dysphagia in patients with AD/ADRD, and she has extensive experience working with caregivers of patients with AD/ADRD in both her clinical rand research roles.
Ashley Goodwin, PhD
Principal Investigator and Co-Investigator
Dr. Goodwin is a Postdoctoral Scientist at the Institute of Health System Science in the Feinstein Institutes for Medical Research. Dr. Goodwin is an exercise physiologist with an expertise in wearable technology to monitor physical activity. Additionally, Dr. Goodwin is an engineer with expertise in building data flow pathways that are useful for the monitoring and analysis of data collected as part of personalized trials, with an emphasis on data integrity.
Codruta Chiuzan, PhD
Co-Investigator
Dr. Chiuzan is an Associate Professor and biostatistician in the Institute of Health System Science, Feinstein Institute for Medical Research. Dr. Chiuzan is an expert in clinical trial design and was the recipient of the Columbia Public Innovation Award for her work in developing statistical methods to improve clinical trial diversity and outcomes using real-world evidence.
Contact Us
Questions, or interested in collaborating? Reach out to us at RoybalTrials@northwell.edu
